Alaabta: 2-phenylacetamide
Qaaciddada molecular: C8H9NO
Miisaanka molecular: 135.17
Magaca Ingiriisiga: Phenylacetamide
Dabeecad: Kariishyo qaabaysan oo caleen ama qolof cad ah.Mp 157-158 ℃, bp 280-290 ℃ (kala-bax).Ku milmay biyo kulul iyo ethanol, wax yar ku milmay biyo qabow, ether, iyo benzene.
Isticmaalka: Dhexdhexaadka daawooyinka sida penicillin iyo phenobarbital.Waxa kale oo loo isticmaalaa diyaarinta phenylacetic acid, xawaashka, iyo sunta cayayaanka.
Habka 1) Masuko F, Katsura T.US 4536599A1.1985.
Ku dar 117.2 g (1.0 mol) phenylacetonitrile (2), 56.1 g oo ah 25% xal potassium hydroxide, 291.5 g of 35% hydrogen peroxide xal aqueous, 1.78 g of benzyltriethylammonium chloride, iyo 351.5 g of isopropanol falcelinta.Walaaq oo ka jawaab 50 ℃ ilaa 4 saacadood.Ka dib marka falcelinta la dhammeeyo, isopropanol waa la uumi-baxa cadaadis la dhimay, la qaboojiyey, la sifeeyay, biyo lagu dhaqay, oo la qalajiyey si loo helo xarun (1) 128.5 g, mp 155 ℃, oo leh wax-soo-saarka 95%.
Habka 2) Furniss BS, Hannaford AJ, Rogers V, et al.Vogel's Textbook of Practical Chemistry.Longman London iyo New York. Daabacaadda afaraad, 1978：518.
Ku dar 100 g (0.85 mol) oo ah phenylacetonitrile (2) iyo 400 mL oo ah hydrochloric acid oo la ururiyey weelka falcelinta.Marka la walaaqayo, ku samee 40 ℃ ilaa 40 daqiiqo, oo kor u qaad heerkulka ilaa 50 ℃.Sii wad falcelinta 30 daqiiqo.Qabooji ilaa 15 ℃ kuna dar 400 ml oo biyo ah oo qabow oo la durduriyay.Ku qaboojinta qubeyska biyaha barafka, nadiifinta kiristaalo.Ku dar adkaha ilaa 50 ml oo biyo ah oo si fiican u walaaq si aad uga saarto phenylacetic acid.Sifee oo qallaji 50-80 ℃ si aad u hesho 95 g oo ah phenylacetamide (1), mp 154-155 ℃, oo leh wax-soo-saar 82%.Dib-u-cistallization oo leh ethanol, mp 156 ℃.
Waqtiga boostada: Abriil-11-2023