1,3-Dihydroxyacetone Hababka Wax Soo Saarka iyo Horudhaca Codsiyada CAS 96-26-4

1,3-Dihydroxyacetone Hordhac

1,3-Dihydroxyacetone waa unug dabiici ah oo leh caanaha molecular C3H6O3, taas oo ah polyhydroxyketose iyo ketose ugu fudud.Muuqaalku waa crystal budo cad, oo si fudud ugu milmaya dareeraha organic sida biyaha, ethanol, ether, iyo acetone.Meesha dhalaalidu waa 75-80 ℃, biyuhuna waa>250g/L (20 ℃).Waxay leedahay dhadhan macaan waxayna ku xasilloon tahay pH 6.0.1,3-Dihydroxyacetone waa sonkorta dhimaysa.Dhammaan monosaccharides (ilaa inta ay jiraan aldehyde bilaash ah ama kooxaha ketone carbonyl) waxay leeyihiin dib u dhac.Dihydroxyacetone waxay la kulantaa shuruudaha kor ku xusan, sidaas darteed waxay ka tirsan tahay qaybta yaraynta sonkorta.

Inta badan waxaa jira hababka isku-dhafka kiimikaad iyo hababka halsano ee microbial.Waxaa jira saddex dariiqo oo kiimiko ah oo loogu talagalay 1,3-dihydroxyacetone: electrocatalysis, oksaydhka katalytic birta, iyo uumiga formaldehyde.Wax soo saarka kiimikaad ee 1,3-dihydroxyacetone ayaa weli ku jira marxaladda cilmi-baarista shaybaarka.Wax soo saarka 1,3-dihydroxyacetone ee habka bayoolojiga ayaa leh faa'iidooyin la taaban karo: xoojinta alaabta sare, heerka beddelka glycerol sare iyo kharashka wax soo saarka hooseeya.Wax soo saarka 1,3-dihydroxyacetone ee Shiinaha iyo dibadda inta badan waxay qaataan habka beddelka microbial ee glycerol.

Habka isku dhafka kiimikada

1. 1,3-dihydroxyacetone waxaa laga soo saaray 1,3-dichloroacetone iyo ethylene glycol sida alaabta ceeriin ee ugu muhiimsan iyada oo loo marayo ilaalinta carbonyl, etherification, hydrogenolysis, iyo hydrolysis.1,3-dichloroacetone iyo ethylene glycol waa la kululeeyaa oo lagu shubaa toluene si loo soo saaro 2,2-dichloromethyl-1,3-dioxolane.Kadib waxay la falgalaan sodium benzylidene ee N, N-dimethylformamide si ay u soo saaraan 2,2-dibenzyloxy-1,3-dioxolane, kaas oo markaa hydrogenated hoos yimaada Pd / C catalysis si ay u soo saaraan 1,3-dioxolane-2,2-dimethanol, kaas oo ayaa markaa lagu shubaa hydrochloric acid si loo soo saaro 1,3-dihydroxyacetone.Qalabka cayriin ee loogu talagalay isku-darka 1,3-dihydroxyacetone iyadoo la adeegsanayo habkan waa sahlan tahay in la helo, xaaladaha falcelintu waa khafiif, Pd / C kicinta ayaa dib loo warshadeyn karaa, taas oo leh qiimaha codsiga muhiimka ah.

2. 1,3-dihydroxyacetone waxaa laga soo saaray 1,3-dichloroacetone iyo methanol iyada oo loo marayo ilaalinta carbonyl, etherification, hydrolysis, iyo falcelinta hydrolysis.1,3-dichloroacetone waxay ka falcelisaa methanol anhydrous xad-dhaaf ah iyadoo ay jirto nuugista si ay u soo saarto 2,2-dimethoxy-1,3-dichloropropane, kaas oo markaa lagu kululeeyo sodium benzylate ee N, N-dimethylformamide si loo soo saaro 2,2-dimethoxy -1,3-dibenzyloxypropane.Ka dib waxaa lagu shubaa hydrogenated hoos yimaada Pd/C catalysis si ay u soo saarto 2,2-dimethoxy-1,3-propanediol, kaas oo markaa lagu hydrolyzed hydrochloric acid si loo soo saaro 1,3-dihydroxyacetone.Jidkani wuxuu bedelayaa difaaca carbonyl ee ethylene glycol ilaa methanol, taasoo sahlaysa in la kala saaro oo la nadiifiyo sheyga 1,3-dihydroxyacetone, kaas oo leh horumarin muhiim ah iyo qiimaha codsiga.

3. Isku-dhafka 1,3-dihydroxyacetone iyadoo la isticmaalayo acetone, methanol, chlorine ama bromine sida alaabta ceeriin ee ugu weyn.Acetone, methanol anhydrous, iyo gaaska chlorine ama bromine ayaa loo isticmaalaa in lagu soo saaro 2,2-dimethoxy-1,3-dichloropropane ama 1,3-dibromo-2,2-dimethoxypropane iyada oo loo marayo hal hab oo dheri ah.Kadibna waxaa lagu dhejiyaa sodium benzylate si ay u soo saaraan 2,2-dimethoxy-1,3-dibenzyloxypropane, ka dibna hydrogenated iyo hydrolyzed si loo soo saaro 1,3-dihydroxyacetone.Jidkani wuxuu leeyahay xaalado falcelin fudud, falcelinta "hal dheri" waxay ka fogaataa isticmaalka qaaliga ah iyo xanaaqa 1,3-dichloroacetone, taasoo ka dhigaysa mid jaban oo qiimo sare u leh horumarka.

Codsiyada

1,3-Dihydroxyacetone waa ketose si dabiici ah u soo baxa kaas oo ah biodegradable, la cuni karo, oo aan sun ku ahayn jidhka bini'aadamka iyo deegaanka.Waa wax-qabad badan oo lagu daro oo loo isticmaali karo isqurxinta, daawooyinka, iyo warshadaha cuntada.

Loo isticmaalo warshadaha qurxinta

1,3-Dihydroxyacetone waxaa inta badan loo isticmaalaa sida maaddo caano ah oo walxaha la isku qurxiyo, gaar ahaan sida muraayadda qorraxda oo leh saameyn gaar ah, taas oo ka hortagi karta uumiga xad-dhaafka ah ee qoyaanka maqaarka, waxayna door ka ciyaaraan qoyaanka, ilaalinta qorraxda, ilaalinta shucaaca UV.Intaa waxaa dheer, kooxaha hawlaha ketone ee DHA waxay la falcelin karaan amino acids iyo kooxaha amino ee keratin maqaarka si ay u sameeyaan polymer brown, taasoo keenta maqaarka dadka inuu soo saaro midab bunni ah oo macmal ah.Sidaa darteed, waxa kale oo loo isticmaali karaa simulant soo-gaadhista cadceedda si loo helo maqaar bunni ah ama bunni ah oo u muuqda mid la mid ah natiijada wakhtiga dheer ee iftiinka qorraxda, taasoo ka dhigaysa mid qurux badan.

Hagaajinta boqolkiiba hilibka doofaarka ee caatada ah

1,3-Dihydroxyacetone waa badeecad dhexdhexaad ah oo ka mid ah dheef-shiid kiimikaadka sonkorta, oo door muhiim ah ka ciyaara habka dheef-shiid kiimikaadka sonkorta, yaraynta dufanka jidhka doofaarka iyo hagaajinta boqolkiiba hilibka caatada ah.Shaqaalaha Sayniska iyo Tiknoolajiyada ee Jabbaan waxay ku muujiyeen tijaabooyin ku darista xaddi gaar ah oo DHA ah iyo isku dhafka pyruvate (calcium milixda) ee quudinta doofaarka (ee miisaanka 3: 1) waxay yareyn kartaa dufanka hilibka doofaarka 12% ilaa 15%, iyo dufanka hilibka lugaha iyo muruqa dhabarka ugu dheer ayaa sidoo kale si isku mid ah loo dhimay, iyadoo la kordhinayo maadada borotiinka.

Cuntooyinka shaqeeya

Kaabista 1,3-dihydroxyacetone (gaar ahaan marka lagu daro pyruvate) waxay hagaajin kartaa heerka dheef-shiid kiimikaadka jirka iyo oksaydhka dufanka dufanka leh, si wax ku ool ah u gubi dufanka si loo yareeyo dufanka jidhka iyo dib u dhigista korodhka miisaanka (saamaynta miisaanka luminta), iyo yaraynta heerka dhacdooyinka cudurada la xiriira.Waxa kale oo ay wanaajin kartaa dareenka insulinta oo ay hoos u dhigi kartaa heerka kolestaroolka balaasmaha ee ay keento cuntada kolestaroolka sare.Kaabista muddada dheer waxay kordhin kartaa heerka isticmaalka sonkorta dhiigga waxayna badbaadin kartaa glycogen muruqa, Ciyaartoyda, waxay hagaajin kartaa waxqabadkooda adkeysiga aerobic.

Isticmaalka kale

1,3-dihydroxyacetone sidoo kale si toos ah ayaa loo isticmaali karaa sida reagent ka hortagga fayraska.Tusaale ahaan, dhaqanka embriyaha digaaga, isticmaalka DHA wuxuu si weyn u joojin karaa infekshanka fayraska distemper digaaga, isagoo dilaya 51% ilaa 100% fayraska.Warshadaha maqaarka, DHA waxaa loo isticmaali karaa sidii wakiilka ilaalinta alaabta maqaarka.Intaa waxaa dheer, waxyaabaha lagu ilaaliyo inta badan ka kooban DHA waxaa loo isticmaali karaa ilaalinta iyo ilaalinta miraha iyo khudaarta, alaabta biyaha, iyo hilibka hilibka.